CENPL-KLHL20 Fusion FISH Probe
The CENPL-KLHL20 Fusion FISH Probe is used to confirm a fusion of the CENPL and KLHL20 genes. The fusion of the CENPL and KLHL20 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CENPL-KLHL20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-RERE | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-REOR | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-REGO | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-REGR | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-REAQ | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-ORRE | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-OROR | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-ORGO | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-ORAQ | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GORE | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GOOR | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GOGO | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GOGR | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GOAQ | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GRRE | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GROR | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GRGO | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GRGR | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-GRAQ | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-AQRE | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-AQOR | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-AQGO | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-AQGR | 20 (40 μL) | 200 μL |
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| CENPL-KLHL20-20-AQAQ | 20 (40 μL) | 200 μL |
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KLHL20 Gene Summary
The protein encoded by this gene is a member of the kelch family of proteins, which is characterized by a 44-56 amino acid repeat motif. The kelch motif appears in many different polypeptide contexts and contains multiple potential protein-protein contact sites. Members of this family are present both throughout the cell and extracellularly, with diverse activities. [provided by RefSeq, Jul 2008]
Gene Name: Kelch Like Family Member 20
Chromosome: CHR1: 173684079 -173755840
Locus: 1q25.1
CENPL Gene Summary
CENPL is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006) [PubMed 16622420].[supplied by OMIM, Mar 2008]
Gene Name: Centromere Protein L
Chromosome: CHR1: 173768687 -173793777
Locus: 1q25.1
Gene Diseases
The CENPL KLHL20 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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