CELF1-BBOX1 Fusion FISH Probe
The CELF1-BBOX1 Fusion FISH Probe is used to confirm a fusion of the CELF1 and BBOX1 genes. The fusion of the CELF1 and BBOX1 genes has been associated with Brain Lower Grade Glioma, and Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CELF1-BBOX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-RERE | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-REOR | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-REGO | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-REGR | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-REAQ | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-ORRE | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-OROR | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-ORGO | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GORE | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GOOR | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GOGO | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GOGR | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GRRE | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GROR | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GRGO | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GRGR | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-AQRE | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-AQOR | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-AQGO | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-AQGR | 20 (40 μL) | 200 μL |
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| CELF1-BBOX1-20-AQAQ | 20 (40 μL) | 200 μL |
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BBOX1 Gene Summary
This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation. [provided by RefSeq, Jul 2008]
Gene Name: Gamma-butyrobetaine Hydroxylase 1
Chromosome: CHR11: 27062508 -27149354
Locus: 11p14.2
CELF1 Gene Summary
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: CUGBP Elav-like Family Member 1
Chromosome: CHR11: 47487488 -47574792
Locus: 11p11.2
Gene Diseases
The CELF1 BBOX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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