CEACAM6-DDX27 Fusion FISH Probe
The CEACAM6-DDX27 Fusion FISH Probe is used to confirm a fusion of the CEACAM6 and DDX27 genes. The fusion of the CEACAM6 and DDX27 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CEACAM6-DDX27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-RERE | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-REOR | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-REGO | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-REGR | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-REAQ | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-ORRE | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-OROR | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-ORGO | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-ORAQ | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GORE | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GOOR | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GOGO | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GOGR | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GOAQ | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GRRE | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GROR | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GRGO | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GRGR | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-GRAQ | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-AQRE | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-AQOR | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-AQGO | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-AQGR | 20 (40 μL) | 200 μL |
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| CEACAM6-DDX27-20-AQAQ | 20 (40 μL) | 200 μL |
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CEACAM6 Gene Summary
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]
Gene Name: Carcinoembryonic Antigen Related Cell Adhesion Molecule 6
Chromosome: CHR19: 42259397 -42276113
Locus: 19q13.2
DDX27 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
Gene Name: DEAD-box Helicase 27
Chromosome: CHR20: 47835831 -47860614
Locus: 20q13.13
Gene Diseases
The CEACAM6 DDX27 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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