CDYL-EEF1E1 Fusion FISH Probe
The CDYL-EEF1E1 Fusion FISH Probe is used to confirm a fusion of the CDYL and EEF1E1 genes. The fusion of the CDYL and EEF1E1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDYL-EEF1E1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-RERE | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-REOR | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-REGO | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-REGR | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-REAQ | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-ORRE | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-OROR | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-ORGO | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GORE | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GOOR | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GOGO | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GOGR | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GRRE | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GROR | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GRGO | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GRGR | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-AQRE | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-AQOR | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-AQGO | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-AQGR | 20 (40 μL) | 200 μL |
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| CDYL-EEF1E1-20-AQAQ | 20 (40 μL) | 200 μL |
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CDYL Gene Summary
Chromodomain Y is a primate-specific Y-chromosomal gene family expressed exclusively in the testis and implicated in infertility. Although the Y-linked genes are testis-specific, this autosomal gene is ubiquitously expressed. The Y-linked genes arose by retrotransposition of an mRNA from this gene, followed by amplification of the retroposed gene. Proteins encoded by this gene superfamily possess a chromodomain, a motif implicated in chromatin binding and gene suppression, and a catalytic domain believed to be involved in histone acetylation. Multiple proteins are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Gene Name: Chromodomain Y Like
Chromosome: CHR6: 4706392 -4955778
Locus: 6p25.1
EEF1E1 Gene Summary
This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010]
Gene Name: Eukaryotic Translation Elongation Factor 1 Epsilon 1
Chromosome: CHR6: 8073592 -8102828
Locus: 6p24.3
Gene Diseases
The CDYL EEF1E1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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