CDKAL1-CRHR2 Fusion FISH Probe
The CDKAL1-CRHR2 Fusion FISH Probe is used to confirm a fusion of the CDKAL1 and CRHR2 genes. The fusion of the CDKAL1 and CRHR2 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDKAL1-CRHR2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-RERE | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-REOR | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-REGO | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-REGR | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-REAQ | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-ORRE | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-OROR | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-ORGO | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GORE | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GOOR | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GOGO | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GOGR | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GRRE | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GROR | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GRGO | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GRGR | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-AQRE | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-AQOR | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-AQGO | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-AQGR | 20 (40 μL) | 200 μL |
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| CDKAL1-CRHR2-20-AQAQ | 20 (40 μL) | 200 μL |
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CRHR2 Gene Summary
The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011]
Gene Name: Corticotropin Releasing Hormone Receptor 2
Chromosome: CHR7: 30691558 -30739719
Locus: 7p14.3
CDKAL1 Gene Summary
The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes. [provided by RefSeq, May 2010]
Gene Name: CDK5 Regulatory Subunit Associated Protein 1 Like 1
Chromosome: CHR6: 20534687 -21232634
Locus: 6p22.3
Gene Diseases
The CDKAL1 CRHR2 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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