CDK7-SH3BGR Fusion FISH Probe
The CDK7-SH3BGR Fusion FISH Probe is used to confirm a fusion of the CDK7 and SH3BGR genes. The fusion of the CDK7 and SH3BGR genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK7-SH3BGR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-RERE | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-REOR | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-REGO | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-REGR | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-REAQ | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-ORRE | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-OROR | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-ORGO | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GORE | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GOOR | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GOGO | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GROR | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GRGR | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-AQRE | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-AQGO | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-AQGR | 20 (40 μL) | 200 μL |
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| CDK7-SH3BGR-20-AQAQ | 20 (40 μL) | 200 μL |
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CDK7 Gene Summary
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
Gene Name: Cyclin Dependent Kinase 7
Chromosome: CHR5: 68530621 -68573257
Locus: 5q13.2
SH3BGR Gene Summary
The SH3 Domain Binding Glutamate Rich Protein (SH3BGR) gene is located on chr21 :40817796-40887433 at 21q22.2.
Gene Name: SH3 Domain Binding Glutamate Rich Protein
Chromosome: CHR21: 40817796 -40887433
Locus: 21q22.2
Gene Diseases
The CDK7 SH3BGR Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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