CDK7-RGS20 Fusion FISH Probe
The CDK7-RGS20 Fusion FISH Probe is used to confirm a fusion of the CDK7 and RGS20 genes. The fusion of the CDK7 and RGS20 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK7-RGS20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-RERE | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-REOR | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-REGO | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-REGR | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-REAQ | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-ORRE | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-OROR | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-ORGO | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GORE | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GOOR | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GOGO | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GROR | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GRGR | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-AQRE | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-AQGO | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-AQGR | 20 (40 μL) | 200 μL |
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| CDK7-RGS20-20-AQAQ | 20 (40 μL) | 200 μL |
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CDK7 Gene Summary
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
Gene Name: Cyclin Dependent Kinase 7
Chromosome: CHR5: 68530621 -68573257
Locus: 5q13.2
RGS20 Gene Summary
The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Regulator Of G Protein Signaling 20
Chromosome: CHR8: 54764367 -54871863
Locus: 8q11.23
Gene Diseases
The CDK7 RGS20 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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