CDK5RAP3-SP2 Fusion FISH Probe
The CDK5RAP3-SP2 Fusion FISH Probe is used to confirm a fusion of the CDK5RAP3 and SP2 genes. The fusion of the CDK5RAP3 and SP2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK5RAP3-SP2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-RERE | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-REOR | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-REGO | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-REGR | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-REAQ | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-ORRE | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-OROR | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-ORGO | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GORE | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GOOR | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GOGO | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GROR | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GRGR | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-AQRE | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-AQGO | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-AQGR | 20 (40 μL) | 200 μL |
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| CDK5RAP3-SP2-20-AQAQ | 20 (40 μL) | 200 μL |
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SP2 Gene Summary
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008]
Gene Name: Sp2 Transcription Factor
Chromosome: CHR17: 45973515 -46006323
Locus: 17q21.32
CDK5RAP3 Gene Summary
This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013]
Gene Name: CDK5 Regulatory Subunit Associated Protein 3
Chromosome: CHR17: 46048428 -46059147
Locus: 17q21.32
Gene Diseases
The CDK5RAP3 SP2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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