CDK2-PAN2 Fusion FISH Probe
The CDK2-PAN2 Fusion FISH Probe is used to confirm a fusion of the CDK2 and PAN2 genes. The fusion of the CDK2 and PAN2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK2-PAN2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-RERE | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-REOR | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-REGO | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-REGR | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-REAQ | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-ORRE | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-OROR | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-ORGO | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GORE | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GOOR | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GOGO | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GROR | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GRGR | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-AQRE | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-AQGO | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-AQGR | 20 (40 μL) | 200 μL |
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| CDK2-PAN2-20-AQAQ | 20 (40 μL) | 200 μL |
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CDK2 Gene Summary
This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Gene Name: Cyclin Dependent Kinase 2
Chromosome: CHR12: 56360555 -56366568
Locus: 12q13.2
PAN2 Gene Summary
This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly(A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: PAN2 Poly(A) Specific Ribonuclease Subunit
Chromosome: CHR12: 56710006 -56727837
Locus: 12q13.3
Gene Diseases
The CDK2 PAN2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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