CDK14-SAV1 Fusion FISH Probe
The CDK14-SAV1 Fusion FISH Probe is used to confirm a fusion of the CDK14 and SAV1 genes. The fusion of the CDK14 and SAV1 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK14-SAV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-RERE | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-REOR | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-REGO | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-REGR | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-REAQ | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-ORRE | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-OROR | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-ORGO | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GORE | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GOOR | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GOGO | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GROR | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GRGR | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-AQRE | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-AQGO | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-AQGR | 20 (40 μL) | 200 μL |
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| CDK14-SAV1-20-AQAQ | 20 (40 μL) | 200 μL |
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CDK14 Gene Summary
PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]
Gene Name: Cyclin Dependent Kinase 14
Chromosome: CHR7: 90338711 -90839904
Locus: 7q21.13
SAV1 Gene Summary
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor. [provided by RefSeq, Aug 2012]
Gene Name: Salvador Family WW Domain Containing Protein 1
Chromosome: CHR14: 51100359 -51135023
Locus: 14q22.1
Gene Diseases
The CDK14 SAV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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