CDK14-ORC5 Fusion FISH Probe
The CDK14-ORC5 Fusion FISH Probe is used to confirm a fusion of the CDK14 and ORC5 genes. The fusion of the CDK14 and ORC5 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK14-ORC5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-RERE | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-REOR | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-REGO | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-REGR | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-REAQ | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-ORRE | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-OROR | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-ORGO | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GORE | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GOOR | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GOGO | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GROR | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GRGR | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-AQRE | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-AQGO | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-AQGR | 20 (40 μL) | 200 μL |
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| CDK14-ORC5-20-AQAQ | 20 (40 μL) | 200 μL |
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ORC5 Gene Summary
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Oct 2010]
Gene Name: Origin Recognition Complex Subunit 5
Chromosome: CHR7: 103766787 -103848495
Locus: 7q22.1-q22.2
CDK14 Gene Summary
PFTK1 is a member of the CDC2 (MIM 116940)-related protein kinase family (Yang and Chen, 2001 [PubMed 11313143]).[supplied by OMIM, Mar 2008]
Gene Name: Cyclin Dependent Kinase 14
Chromosome: CHR7: 90338711 -90839904
Locus: 7q21.13
Gene Diseases
The CDK14 ORC5 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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