CDK13-TAX1BP1 Fusion FISH Probe
The CDK13-TAX1BP1 Fusion FISH Probe is used to confirm a fusion of the CDK13 and TAX1BP1 genes. The fusion of the CDK13 and TAX1BP1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK13-TAX1BP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-RERE | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-REOR | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-REGO | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-REGR | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-REAQ | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-ORRE | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-OROR | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-ORGO | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GORE | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GOOR | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GOGO | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GROR | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GRGR | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-AQRE | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-AQGO | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-AQGR | 20 (40 μL) | 200 μL |
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| CDK13-TAX1BP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CDK13 Gene Summary
The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described.[provided by RefSeq, Dec 2009]
Gene Name: Cyclin Dependent Kinase 13
Chromosome: CHR7: 39989958 -40136733
Locus: 7p14.1
TAX1BP1 Gene Summary
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
Gene Name: Tax1 Binding Protein 1
Chromosome: CHR7: 27778991 -27869386
Locus: 7p15.2
Gene Diseases
The CDK13 TAX1BP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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