CDK13-DDX56 Fusion FISH Probe
The CDK13-DDX56 Fusion FISH Probe is used to confirm a fusion of the CDK13 and DDX56 genes. The fusion of the CDK13 and DDX56 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK13-DDX56-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-RERE | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-REOR | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-REGO | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-REGR | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-REAQ | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-ORRE | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-OROR | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-ORGO | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GORE | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GOOR | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GOGO | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GROR | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GRGR | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-AQRE | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-AQGO | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-AQGR | 20 (40 μL) | 200 μL |
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| CDK13-DDX56-20-AQAQ | 20 (40 μL) | 200 μL |
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CDK13 Gene Summary
The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described.[provided by RefSeq, Dec 2009]
Gene Name: Cyclin Dependent Kinase 13
Chromosome: CHR7: 39989958 -40136733
Locus: 7p14.1
DDX56 Gene Summary
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene shows ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles. This gene may be involved in ribosome synthesis, most likely during assembly of the large 60S ribosomal subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Gene Name: DEAD-box Helicase 56
Chromosome: CHR7: 44605402 -44614137
Locus: 7p13
Gene Diseases
The CDK13 DDX56 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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