CDK12-CACNB1 Fusion FISH Probe
The CDK12-CACNB1 Fusion FISH Probe is used to confirm a fusion of the CDK12 and CACNB1 genes. The fusion of the CDK12 and CACNB1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDK12-CACNB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-RERE | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-REOR | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-REGO | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-REGR | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-REAQ | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-ORRE | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-OROR | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-ORGO | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GORE | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GOOR | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GOGO | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GOGR | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GRRE | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GROR | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GRGO | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GRGR | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-AQRE | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-AQOR | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-AQGO | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-AQGR | 20 (40 μL) | 200 μL |
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| CDK12-CACNB1-20-AQAQ | 20 (40 μL) | 200 μL |
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CACNB1 Gene Summary
The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Calcium Voltage-gated Channel Auxiliary Subunit Beta 1
Chromosome: CHR17: 37329708 -37353901
Locus: 17q12
CDK12 Gene Summary
The Cyclin Dependent Kinase 12 (CDK12) gene is located on chr17 :37617738-37690800 at 17q12.
Gene Name: Cyclin Dependent Kinase 12
Chromosome: CHR17: 37617738 -37690800
Locus: 17q12
Gene Diseases
The CDK12 CACNB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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