CDIPT-SEZ6L2 Fusion FISH Probe
The CDIPT-SEZ6L2 Fusion FISH Probe is used to confirm a fusion of the CDIPT and SEZ6L2 genes. The fusion of the CDIPT and SEZ6L2 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDIPT-SEZ6L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-RERE | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-REOR | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-REGO | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-REGR | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-REAQ | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-ORRE | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-OROR | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-ORGO | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GORE | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GOOR | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GOGO | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GOGR | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GRRE | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GROR | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GRGO | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GRGR | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-AQRE | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-AQOR | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-AQGO | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-AQGR | 20 (40 μL) | 200 μL |
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| CDIPT-SEZ6L2-20-AQAQ | 20 (40 μL) | 200 μL |
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CDIPT Gene Summary
Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Gene Name: CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Chromosome: CHR16: 29869677 -29874578
Locus: 16p11.2
SEZ6L2 Gene Summary
This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Gene Name: Seizure Related 6 Homolog Like 2
Chromosome: CHR16: 29882479 -29910585
Locus: 16p11.2
Gene Diseases
The CDIPT SEZ6L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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