CDH4-NLRP9 Fusion FISH Probe
The CDH4-NLRP9 Fusion FISH Probe is used to confirm a fusion of the CDH4 and NLRP9 genes. The fusion of the CDH4 and NLRP9 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDH4-NLRP9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-RERE | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-REOR | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-REGO | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-REGR | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-REAQ | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-ORRE | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-OROR | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-ORGO | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GORE | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GOOR | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GOGO | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GOGR | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GRRE | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GROR | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GRGO | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GRGR | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-AQRE | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-AQOR | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-AQGO | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-AQGR | 20 (40 μL) | 200 μL |
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| CDH4-NLRP9-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH4 Gene Summary
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Cadherin 4
Chromosome: CHR20: 59827558 -60512299
Locus: 20q13.33
NLRP9 Gene Summary
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq, Jul 2008]
Gene Name: NLR Family Pyrin Domain Containing 9
Chromosome: CHR19: 56219797 -56249768
Locus: 19q13.42
Gene Diseases
The CDH4 NLRP9 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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