CDH4-FGF16 Fusion FISH Probe
The CDH4-FGF16 Fusion FISH Probe is used to confirm a fusion of the CDH4 and FGF16 genes. The fusion of the CDH4 and FGF16 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDH4-FGF16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-RERE | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-REOR | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-REGO | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-REGR | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-REAQ | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-ORRE | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-OROR | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-ORGO | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GORE | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GOOR | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GOGO | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GOGR | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GRRE | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GROR | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GRGO | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GRGR | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-AQRE | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-AQOR | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-AQGO | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-AQGR | 20 (40 μL) | 200 μL |
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| CDH4-FGF16-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH4 Gene Summary
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Cadherin 4
Chromosome: CHR20: 59827558 -60512299
Locus: 20q13.33
FGF16 Gene Summary
This gene encodes a member of a family of proteins that are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene is expressed in cardiac cells and is required for proper heart development. Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion. [provided by RefSeq, Mar 2014]
Gene Name: Fibroblast Growth Factor 16
Chromosome: CHRX: 76709646 -76712013
Locus: Xq21.1
Gene Diseases
The CDH4 FGF16 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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