CDH13-TXNDC11 Fusion FISH Probe
The CDH13-TXNDC11 Fusion FISH Probe is used to confirm a fusion of the CDH13 and TXNDC11 genes. The fusion of the CDH13 and TXNDC11 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDH13-TXNDC11-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-RERE | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-REOR | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-REGO | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-REGR | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-REAQ | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-ORRE | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-OROR | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-ORGO | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GORE | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GOOR | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GOGO | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GOGR | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GRRE | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GROR | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GRGO | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GRGR | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-AQRE | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-AQOR | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-AQGO | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-AQGR | 20 (40 μL) | 200 μL |
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| CDH13-TXNDC11-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH13 Gene Summary
This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]
Gene Name: Cadherin 13
Chromosome: CHR16: 82660398 -83830215
Locus: 16q23.3
TXNDC11 Gene Summary
The Thioredoxin Domain Containing 11 (TXNDC11) gene is located on chr16 :11772942-11836648 at 16p13.13.
Gene Name: Thioredoxin Domain Containing 11
Chromosome: CHR16: 11772942 -11836648
Locus: 16p13.13
Gene Diseases
The CDH13 TXNDC11 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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