CDH11-PRC1 Fusion FISH Probe
The CDH11-PRC1 Fusion FISH Probe is used to confirm a fusion of the CDH11 and PRC1 genes. The fusion of the CDH11 and PRC1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDH11-PRC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-RERE | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-REOR | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-REGO | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-REGR | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-REAQ | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-ORRE | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-OROR | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-ORGO | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GORE | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GOOR | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GOGO | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GOGR | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GRRE | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GROR | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GRGO | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GRGR | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-AQRE | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-AQOR | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-AQGO | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-AQGR | 20 (40 μL) | 200 μL |
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| CDH11-PRC1-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH11 Gene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Gene Name: Cadherin 11
Chromosome: CHR16: 64980682 -65155919
Locus: 16q21
PRC1 Gene Summary
This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Gene Name: Protein Regulator Of Cytokinesis 1
Chromosome: CHR15: 91509267 -91537804
Locus: 15q26.1
Gene Diseases
The CDH11 PRC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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