CDH11-KIFC3 Fusion FISH Probe
The CDH11-KIFC3 Fusion FISH Probe is used to confirm a fusion of the CDH11 and KIFC3 genes. The fusion of the CDH11 and KIFC3 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDH11-KIFC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-RERE | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-REOR | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-REGO | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-REGR | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-REAQ | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-ORRE | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-OROR | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-ORGO | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GORE | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GOOR | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GOGO | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GOGR | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GRRE | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GROR | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GRGO | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GRGR | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-AQRE | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-AQOR | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-AQGO | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-AQGR | 20 (40 μL) | 200 μL |
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| CDH11-KIFC3-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH11 Gene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]
Gene Name: Cadherin 11
Chromosome: CHR16: 64980682 -65155919
Locus: 16q21
KIFC3 Gene Summary
This gene encodes a member of the kinesin-14 family of microtubule motors. Members of this family play a role in the formation, maintenance and remodeling of the bipolar mitotic spindle. The protein encoded by this gene has cytoplasmic functions in the interphase cells. It may also be involved in the final stages of cytokinesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
Gene Name: Kinesin Family Member C3
Chromosome: CHR16: 57792128 -57836439
Locus: 16q21
Gene Diseases
The CDH11 KIFC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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