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CDH1-TRHDE Fusion FISH Probe

The CDH1-TRHDE Fusion FISH Probe is used to confirm a fusion of the CDH1 and TRHDE genes. The fusion of the CDH1 and TRHDE genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CDH1-TRHDE-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CDH1-TRHDE-20-RERE 20 (40 μL) 200 μL
CDH1-TRHDE-20-REOR 20 (40 μL) 200 μL
CDH1-TRHDE-20-REGO 20 (40 μL) 200 μL
CDH1-TRHDE-20-REGR 20 (40 μL) 200 μL
CDH1-TRHDE-20-REAQ 20 (40 μL) 200 μL
CDH1-TRHDE-20-ORRE 20 (40 μL) 200 μL
CDH1-TRHDE-20-OROR 20 (40 μL) 200 μL
CDH1-TRHDE-20-ORGO 20 (40 μL) 200 μL
CDH1-TRHDE-20-ORAQ 20 (40 μL) 200 μL
CDH1-TRHDE-20-GORE 20 (40 μL) 200 μL
CDH1-TRHDE-20-GOOR 20 (40 μL) 200 μL
CDH1-TRHDE-20-GOGO 20 (40 μL) 200 μL
CDH1-TRHDE-20-GOGR 20 (40 μL) 200 μL
CDH1-TRHDE-20-GOAQ 20 (40 μL) 200 μL
CDH1-TRHDE-20-GRRE 20 (40 μL) 200 μL
CDH1-TRHDE-20-GROR 20 (40 μL) 200 μL
CDH1-TRHDE-20-GRGO 20 (40 μL) 200 μL
CDH1-TRHDE-20-GRGR 20 (40 μL) 200 μL
CDH1-TRHDE-20-GRAQ 20 (40 μL) 200 μL
CDH1-TRHDE-20-AQRE 20 (40 μL) 200 μL
CDH1-TRHDE-20-AQOR 20 (40 μL) 200 μL
CDH1-TRHDE-20-AQGO 20 (40 μL) 200 μL
CDH1-TRHDE-20-AQGR 20 (40 μL) 200 μL
CDH1-TRHDE-20-AQAQ 20 (40 μL) 200 μL

CDH1 Gene Summary

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]

Gene Name: Cadherin 1

Chromosome: CHR16: 68771194 -68869444

Locus: 16q22.1

TRHDE Gene Summary

This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.[provided by RefSeq, Dec 2008]

Gene Name: Thyrotropin Releasing Hormone Degrading Enzyme

Chromosome: CHR12: 72666528 -73059422

Locus: 12q21.1

Gene Diseases

The CDH1 TRHDE Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.