CDC42EP4-COMMD1 Fusion FISH Probe
The CDC42EP4-COMMD1 Fusion FISH Probe is used to confirm a fusion of the CDC42EP4 and COMMD1 genes. The fusion of the CDC42EP4 and COMMD1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDC42EP4-COMMD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-RERE | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-REOR | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-REGO | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-REGR | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-REAQ | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-ORRE | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-OROR | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-ORGO | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GORE | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GOOR | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GOGO | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GOGR | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GRRE | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GROR | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GRGO | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GRGR | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-AQRE | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-AQOR | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-AQGO | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-AQGR | 20 (40 μL) | 200 μL |
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| CDC42EP4-COMMD1-20-AQAQ | 20 (40 μL) | 200 μL |
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CDC42EP4 Gene Summary
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq, Jul 2008]
Gene Name: CDC42 Effector Protein 4
Chromosome: CHR17: 71279762 -71308143
Locus: 17q25.1
COMMD1 Gene Summary
COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005 [PubMed 16267171]).[supplied by OMIM, Sep 2009]
Gene Name: Copper Metabolism Domain Containing 1
Chromosome: CHR2: 62132802 -62363205
Locus: 2p15
Gene Diseases
The CDC42EP4 COMMD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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