CDC42BPB-ZFYVE1 Fusion FISH Probe
The CDC42BPB-ZFYVE1 Fusion FISH Probe is used to confirm a fusion of the CDC42BPB and ZFYVE1 genes. The fusion of the CDC42BPB and ZFYVE1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDC42BPB-ZFYVE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CDC42BPB-ZFYVE1-20-AQAQ | 20 (40 μL) | 200 μL |
|
CDC42BPB Gene Summary
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase-related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization. [provided by RefSeq, Jul 2008]
Gene Name: CDC42 Binding Protein Kinase Beta
Chromosome: CHR14: 103398715 -103523742
Locus: 14q32.32
ZFYVE1 Gene Summary
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Name: Zinc Finger FYVE-type Containing 1
Chromosome: CHR14: 73436158 -73493920
Locus: 14q24.2
Gene Diseases
The CDC42BPB ZFYVE1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|