CDC42BPA-EPRS Fusion FISH Probe
The CDC42BPA-EPRS Fusion FISH Probe is used to confirm a fusion of the CDC42BPA and EPRS genes. The fusion of the CDC42BPA and EPRS genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CDC42BPA-EPRS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-RERE | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-REOR | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-REGO | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-REGR | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-REAQ | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-ORRE | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-OROR | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-ORGO | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-ORAQ | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GORE | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GOOR | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GOGO | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GOGR | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GOAQ | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GRRE | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GROR | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GRGO | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GRGR | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-GRAQ | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-AQRE | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-AQOR | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-AQGO | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-AQGR | 20 (40 μL) | 200 μL |
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| CDC42BPA-EPRS-20-AQAQ | 20 (40 μL) | 200 μL |
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EPRS Gene Summary
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species. Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Glutamyl-prolyl-tRNA Synthetase
Chromosome: CHR1: 220141941 -220220000
Locus: 1q41
CDC42BPA Gene Summary
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008]
Gene Name: CDC42 Binding Protein Kinase Alpha
Chromosome: CHR1: 227177565 -227505826
Locus: 1q42.13
Gene Diseases
The CDC42BPA EPRS Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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