CD81-TYK2 Fusion FISH Probe
The CD81-TYK2 Fusion FISH Probe is used to confirm a fusion of the CD81 and TYK2 genes. The fusion of the CD81 and TYK2 genes has been associated with Thymoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD81-TYK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-RERE | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-REOR | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-REGO | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-REGR | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-REAQ | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-ORRE | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-OROR | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-ORGO | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GORE | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GOOR | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GOGO | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GOGR | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GRRE | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GROR | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GRGO | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GRGR | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-AQRE | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-AQOR | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-AQGO | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-AQGR | 20 (40 μL) | 200 μL |
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| CD81-TYK2-20-AQAQ | 20 (40 μL) | 200 μL |
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CD81 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Name: CD81 Molecule
Chromosome: CHR11: 2398546 -2418649
Locus: 11p15.5
TYK2 Gene Summary
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
Gene Name: Tyrosine Kinase 2
Chromosome: CHR19: 10461203 -10491248
Locus: 19p13.2
Gene Diseases
The CD81 TYK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Thymoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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