CD81-SUPT16H Fusion FISH Probe
The CD81-SUPT16H Fusion FISH Probe is used to confirm a fusion of the CD81 and SUPT16H genes. The fusion of the CD81 and SUPT16H genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD81-SUPT16H-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-RERE | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-REOR | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-REGO | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-REGR | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-REAQ | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-ORRE | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-OROR | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-ORGO | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GORE | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GOOR | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GOGO | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GOGR | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GRRE | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GROR | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GRGO | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GRGR | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-AQRE | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-AQOR | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-AQGO | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-AQGR | 20 (40 μL) | 200 μL |
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| CD81-SUPT16H-20-AQAQ | 20 (40 μL) | 200 μL |
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CD81 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Name: CD81 Molecule
Chromosome: CHR11: 2398546 -2418649
Locus: 11p15.5
SUPT16H Gene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009]
Gene Name: SPT16 Homolog, Facilitates Chromatin Remodeling Subunit
Chromosome: CHR14: 21819630 -21852425
Locus: 14q11.2
Gene Diseases
The CD81 SUPT16H Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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