CD81-ARMC3 Fusion FISH Probe
The CD81-ARMC3 Fusion FISH Probe is used to confirm a fusion of the CD81 and ARMC3 genes. The fusion of the CD81 and ARMC3 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD81-ARMC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-RERE | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-REOR | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-REGO | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-REGR | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-REAQ | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-ORRE | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-OROR | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-ORGO | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GORE | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GOOR | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GOGO | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GOGR | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GRRE | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GROR | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GRGO | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GRGR | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-AQRE | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-AQOR | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-AQGO | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-AQGR | 20 (40 μL) | 200 μL |
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| CD81-ARMC3-20-AQAQ | 20 (40 μL) | 200 μL |
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CD81 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Name: CD81 Molecule
Chromosome: CHR11: 2398546 -2418649
Locus: 11p15.5
ARMC3 Gene Summary
Armadillo/beta-catenin (CTNNB1; MIM 116806)-like (ARM) domains are imperfect 45-amino acid repeats involved in protein-protein interactions. ARM domain-containing proteins, such as ARMC3, function in signal transduction, development, cell adhesion and mobility, and tumor initiation and metastasis (Li et al., 2006 [PubMed 16915934]).[supplied by OMIM, Mar 2008]
Gene Name: Armadillo Repeat Containing 3
Chromosome: CHR10: 23216953 -23326514
Locus: 10p12.2
Gene Diseases
The CD81 ARMC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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