CD63-OS9 Fusion FISH Probe
The CD63-OS9 Fusion FISH Probe is used to confirm a fusion of the CD63 and OS9 genes. The fusion of the CD63 and OS9 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD63-OS9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-RERE | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-REOR | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-REGO | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-REGR | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-OROR | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GORE | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GROR | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| CD63-OS9-20-AQAQ | 20 (40 μL) | 200 μL |
|
CD63 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Gene Name: CD63 Molecule
Chromosome: CHR12: 56119229 -56122910
Locus: 12q13.2
OS9 Gene Summary
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: OS9, Endoplasmic Reticulum Lectin
Chromosome: CHR12: 58087737 -58115340
Locus: 12q13.3-q14.1
Gene Diseases
The CD63 OS9 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|