CD63-EIF2AK2 Fusion FISH Probe
The CD63-EIF2AK2 Fusion FISH Probe is used to confirm a fusion of the CD63 and EIF2AK2 genes. The fusion of the CD63 and EIF2AK2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD63-EIF2AK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-RERE | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-REOR | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-REGO | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-REGR | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-REAQ | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-ORRE | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-OROR | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-ORGO | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GORE | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GOOR | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GOGO | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GOGR | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GRRE | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GROR | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GRGO | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GRGR | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-AQRE | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-AQOR | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-AQGO | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-AQGR | 20 (40 μL) | 200 μL |
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| CD63-EIF2AK2-20-AQAQ | 20 (40 μL) | 200 μL |
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CD63 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Gene Name: CD63 Molecule
Chromosome: CHR12: 56119229 -56122910
Locus: 12q13.2
EIF2AK2 Gene Summary
The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2
Chromosome: CHR2: 37333698 -37384190
Locus: 2p22.2
Gene Diseases
The CD63 EIF2AK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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