CD63-AARS Fusion FISH Probe
The CD63-AARS Fusion FISH Probe is used to confirm a fusion of the CD63 and AARS genes. The fusion of the CD63 and AARS genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD63-AARS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-RERE | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-REOR | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-REGO | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-REGR | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-REAQ | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-ORRE | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-OROR | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-ORGO | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GORE | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GOOR | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GOGO | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GOGR | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GRRE | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GROR | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GRGO | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GRGR | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-AQRE | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-AQOR | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-AQGO | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-AQGR | 20 (40 μL) | 200 μL |
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| CD63-AARS-20-AQAQ | 20 (40 μL) | 200 μL |
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AARS Gene Summary
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008]
Gene Name: Alanyl-tRNA Synthetase
Chromosome: CHR16: 70286296 -70323412
Locus: 16q22.1
CD63 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012]
Gene Name: CD63 Molecule
Chromosome: CHR12: 56119229 -56122910
Locus: 12q13.2
Gene Diseases
The CD63 AARS Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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