CD55-NEK2 Fusion FISH Probe
The CD55-NEK2 Fusion FISH Probe is used to confirm a fusion of the CD55 and NEK2 genes. The fusion of the CD55 and NEK2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD55-NEK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-RERE | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-REOR | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-REGO | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-REGR | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-REAQ | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-ORRE | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-OROR | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-ORGO | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GORE | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GOOR | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GOGO | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GOGR | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GRRE | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GROR | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GRGO | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GRGR | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-AQRE | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-AQOR | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-AQGO | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-AQGR | 20 (40 μL) | 200 μL |
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| CD55-NEK2-20-AQAQ | 20 (40 μL) | 200 μL |
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CD55 Gene Summary
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014]
Gene Name: CD55 Molecule (Cromer Blood Group)
Chromosome: CHR1: 207494816 -207534311
Locus: 1q32.2
NEK2 Gene Summary
This gene encodes a serine/threonine-protein kinase that is involved in mitotic regulation. This protein is localized to the centrosome, and undetectable during G1 phase, but accumulates progressively throughout the S phase, reaching maximal levels in late G2 phase. Alternatively spliced transcript variants encoding different isoforms with distinct C-termini have been noted for this gene. [provided by RefSeq, Feb 2011]
Gene Name: NIMA Related Kinase 2
Chromosome: CHR1: 211831598 -211848972
Locus: 1q32.3
Gene Diseases
The CD55 NEK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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