CD55-C4BPA Fusion FISH Probe
The CD55-C4BPA Fusion FISH Probe is used to confirm a fusion of the CD55 and C4BPA genes. The fusion of the CD55 and C4BPA genes has been associated with Lung Adenocarcinoma, and Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD55-C4BPA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-RERE | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-REOR | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-REGO | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-REGR | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-REAQ | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-ORRE | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-OROR | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-ORGO | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GORE | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GOOR | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GOGO | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GOGR | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GRRE | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GROR | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GRGO | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GRGR | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-AQRE | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-AQOR | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-AQGO | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-AQGR | 20 (40 μL) | 200 μL |
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| CD55-C4BPA-20-AQAQ | 20 (40 μL) | 200 μL |
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C4BPA Gene Summary
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]
Gene Name: Complement Component 4 Binding Protein Alpha
Chromosome: CHR1: 207277606 -207318317
Locus: 1q32.2
CD55 Gene Summary
This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014]
Gene Name: CD55 Molecule (Cromer Blood Group)
Chromosome: CHR1: 207494816 -207534311
Locus: 1q32.2
Gene Diseases
The CD55 C4BPA Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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