CD44-EXT2 Fusion FISH Probe
The CD44-EXT2 Fusion FISH Probe is used to confirm a fusion of the CD44 and EXT2 genes. The fusion of the CD44 and EXT2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD44-EXT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-RERE | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-REOR | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-REGO | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-REGR | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-REAQ | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-ORRE | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-OROR | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-ORGO | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GORE | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GOOR | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GOGO | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GOGR | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GRRE | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GROR | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GRGO | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GRGR | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-AQRE | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-AQOR | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-AQGO | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-AQGR | 20 (40 μL) | 200 μL |
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| CD44-EXT2-20-AQAQ | 20 (40 μL) | 200 μL |
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CD44 Gene Summary
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Gene Name: CD44 Molecule (Indian Blood Group)
Chromosome: CHR11: 35160416 -35253949
Locus: 11p13
EXT2 Gene Summary
This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Exostosin Glycosyltransferase 2
Chromosome: CHR11: 44117098 -44266980
Locus: 11p11.2
Gene Diseases
The CD44 EXT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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