CD2AP-SLC25A13 Fusion FISH Probe
The CD2AP-SLC25A13 Fusion FISH Probe is used to confirm a fusion of the CD2AP and SLC25A13 genes. The fusion of the CD2AP and SLC25A13 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD2AP-SLC25A13-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-RERE | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-REOR | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-REGO | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-REGR | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-REAQ | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-ORRE | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-OROR | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-ORGO | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GORE | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GOOR | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GOGO | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GOGR | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GRRE | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GROR | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GRGO | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GRGR | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-AQRE | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-AQOR | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-AQGO | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-AQGR | 20 (40 μL) | 200 μL |
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| CD2AP-SLC25A13-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC25A13 Gene Summary
This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Name: Solute Carrier Family 25 Member 13
Chromosome: CHR7: 95749531 -95951459
Locus: 7q21.3
CD2AP Gene Summary
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008]
Gene Name: CD2 Associated Protein
Chromosome: CHR6: 47445524 -47594996
Locus: 6p12.3
Gene Diseases
The CD2AP SLC25A13 Fusion has been associated with the following diseases:
| Disease Name |
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| Rectum Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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