CD276-PARP16 Fusion FISH Probe
The CD276-PARP16 Fusion FISH Probe is used to confirm a fusion of the CD276 and PARP16 genes. The fusion of the CD276 and PARP16 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD276-PARP16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-RERE | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-REOR | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-REGO | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-REGR | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-REAQ | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-ORRE | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-OROR | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-ORGO | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GORE | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GOOR | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GOGO | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GOGR | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GRRE | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GROR | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GRGO | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GRGR | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-AQRE | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-AQOR | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-AQGO | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-AQGR | 20 (40 μL) | 200 μL |
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| CD276-PARP16-20-AQAQ | 20 (40 μL) | 200 μL |
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PARP16 Gene Summary
The Poly(ADP-ribose) Polymerase Family Member 16 (PARP16) gene is located on chr15 :65550436-65579018 at 15q22.31.
Gene Name: Poly(ADP-ribose) Polymerase Family Member 16
Chromosome: CHR15: 65550436 -65579018
Locus: 15q22.31
CD276 Gene Summary
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: CD276 Molecule
Chromosome: CHR15: 73976621 -74006859
Locus: 15q24.1
Gene Diseases
The CD276 PARP16 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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