CD274-IGFBPL1 Fusion FISH Probe
The CD274-IGFBPL1 Fusion FISH Probe is used to confirm a fusion of the CD274 and IGFBPL1 genes. The fusion of the CD274 and IGFBPL1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD274-IGFBPL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-RERE | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-REOR | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-REGO | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-REGR | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-REAQ | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-ORRE | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-OROR | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-ORGO | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GORE | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GOOR | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GOGO | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GOGR | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GRRE | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GROR | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GRGO | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GRGR | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-AQRE | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-AQOR | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-AQGO | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-AQGR | 20 (40 μL) | 200 μL |
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| CD274-IGFBPL1-20-AQAQ | 20 (40 μL) | 200 μL |
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CD274 Gene Summary
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Gene Name: CD274 Molecule
Chromosome: CHR9: 5450502 -5470567
Locus: 9p24.1
IGFBPL1 Gene Summary
The Insulin Like Growth Factor Binding Protein Like 1 (IGFBPL1) gene is located on chr9 :38408990-38424444 at 9p13.1.
Gene Name: Insulin Like Growth Factor Binding Protein Like 1
Chromosome: CHR9: 38408990 -38424444
Locus: 9p13.1
Gene Diseases
The CD274 IGFBPL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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