CD151-EPS8L2 Fusion FISH Probe
The CD151-EPS8L2 Fusion FISH Probe is used to confirm a fusion of the CD151 and EPS8L2 genes. The fusion of the CD151 and EPS8L2 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CD151-EPS8L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-RERE | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-REOR | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-REGO | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-REGR | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-REAQ | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-ORRE | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-OROR | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-ORGO | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GORE | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GOOR | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GOGO | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GOGR | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GRRE | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GROR | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GRGO | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GRGR | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-AQRE | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-AQOR | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-AQGO | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-AQGR | 20 (40 μL) | 200 μL |
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| CD151-EPS8L2-20-AQAQ | 20 (40 μL) | 200 μL |
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CD151 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: CD151 Molecule (Raph Blood Group)
Chromosome: CHR11: 832951 -838835
Locus: 11p15.5
EPS8L2 Gene Summary
This gene encodes a member of the EPS8 gene family. The encoded protein, like other members of the family, is thought to link growth factor stimulation to actin organization, generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling. [provided by RefSeq, Dec 2008]
Gene Name: EPS8 Like 2
Chromosome: CHR11: 706119 -727727
Locus: 11p15.5
Gene Diseases
The CD151 EPS8L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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