CCT2-CPM Fusion FISH Probe
The CCT2-CPM Fusion FISH Probe is used to confirm a fusion of the CCT2 and CPM genes. The fusion of the CCT2 and CPM genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCT2-CPM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-RERE | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-REOR | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-REGO | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-REGR | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-REAQ | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-ORRE | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-OROR | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-ORGO | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GORE | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GOOR | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GOGO | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GOGR | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GRRE | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GROR | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GRGO | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GRGR | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-AQRE | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-AQOR | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-AQGO | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-AQGR | 20 (40 μL) | 200 μL |
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| CCT2-CPM-20-AQAQ | 20 (40 μL) | 200 μL |
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CPM Gene Summary
The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Carboxypeptidase M
Chromosome: CHR12: 69244955 -69357020
Locus: 12q15
CCT2 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Gene Name: Chaperonin Containing TCP1 Subunit 2
Chromosome: CHR12: 69979207 -69995357
Locus: 12q15
Gene Diseases
The CCT2 CPM Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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