CCNY-PTPRD Fusion FISH Probe
The CCNY-PTPRD Fusion FISH Probe is used to confirm a fusion of the CCNY and PTPRD genes. The fusion of the CCNY and PTPRD genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCNY-PTPRD-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-RERE | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-REOR | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-REGO | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-REGR | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-REAQ | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-ORRE | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-OROR | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-ORGO | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GORE | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GOOR | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GOGO | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GOGR | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GRRE | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GROR | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GRGO | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GRGR | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-AQRE | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-AQOR | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-AQGO | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-AQGR | 20 (40 μL) | 200 μL |
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| CCNY-PTPRD-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRD Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type D
Chromosome: CHR9: 8314245 -10612723
Locus: 9p24.1-p23
CCNY Gene Summary
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009]
Gene Name: Cyclin Y
Chromosome: CHR10: 35535952 -35860847
Locus: 10p11.21
Gene Diseases
The CCNY PTPRD Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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