CCNY-CREM Fusion FISH Probe
The CCNY-CREM Fusion FISH Probe is used to confirm a fusion of the CCNY and CREM genes. The fusion of the CCNY and CREM genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCNY-CREM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-RERE | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-REOR | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-REGO | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-REGR | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-REAQ | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-ORRE | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-OROR | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-ORGO | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GORE | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GOOR | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GOGO | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GOGR | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GRRE | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GROR | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GRGO | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GRGR | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-AQRE | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-AQOR | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-AQGO | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-AQGR | 20 (40 μL) | 200 μL |
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| CCNY-CREM-20-AQAQ | 20 (40 μL) | 200 μL |
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CREM Gene Summary
This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008]
Gene Name: CAMP Responsive Element Modulator
Chromosome: CHR10: 35415800 -35501886
Locus: 10p11.21
CCNY Gene Summary
Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).[supplied by OMIM, May 2009]
Gene Name: Cyclin Y
Chromosome: CHR10: 35535952 -35860847
Locus: 10p11.21
Gene Diseases
The CCNY CREM Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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