CCNF-NOL4 Fusion FISH Probe
The CCNF-NOL4 Fusion FISH Probe is used to confirm a fusion of the CCNF and NOL4 genes. The fusion of the CCNF and NOL4 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCNF-NOL4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-RERE | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-REOR | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-REGO | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-REGR | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-REAQ | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-ORRE | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-OROR | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-ORGO | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GORE | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GOOR | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GOGO | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GOGR | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GRRE | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GROR | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GRGO | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GRGR | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-AQRE | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-AQOR | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-AQGO | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-AQGR | 20 (40 μL) | 200 μL |
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| CCNF-NOL4-20-AQAQ | 20 (40 μL) | 200 μL |
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CCNF Gene Summary
This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it was one of the first proteins in which the F-box motif was identified. [provided by RefSeq, Jul 2008]
Gene Name: Cyclin F
Chromosome: CHR16: 2479394 -2508859
Locus: 16p13.3
NOL4 Gene Summary
The Nucleolar Protein 4 (NOL4) gene is located on chr18 :31431063-31803515 at 18q12.1.
Gene Name: Nucleolar Protein 4
Chromosome: CHR18: 31431063 -31803515
Locus: 18q12.1
Gene Diseases
The CCNF NOL4 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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