CCNB2-TCF12 Fusion FISH Probe
The CCNB2-TCF12 Fusion FISH Probe is used to confirm a fusion of the CCNB2 and TCF12 genes. The fusion of the CCNB2 and TCF12 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCNB2-TCF12-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-RERE | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-REOR | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-REGO | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-REGR | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-REAQ | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-ORRE | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-OROR | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-ORGO | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GORE | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GOOR | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GOGO | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GOGR | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GRRE | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GROR | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GRGO | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GRGR | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-AQRE | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-AQOR | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-AQGO | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-AQGR | 20 (40 μL) | 200 μL |
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| CCNB2-TCF12-20-AQAQ | 20 (40 μL) | 200 μL |
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TCF12 Gene Summary
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: Transcription Factor 12
Chromosome: CHR15: 57210832 -57580714
Locus: 15q21.3
CCNB2 Gene Summary
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]
Gene Name: Cyclin B2
Chromosome: CHR15: 59397283 -59417244
Locus: 15q22.2
Gene Diseases
The CCNB2 TCF12 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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