CCL14-MYH10 Fusion FISH Probe
The CCL14-MYH10 Fusion FISH Probe is used to confirm a fusion of the CCL14 and MYH10 genes. The fusion of the CCL14 and MYH10 genes has been associated with Cholangiocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCL14-MYH10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-RERE | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-REOR | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-REGO | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-REGR | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-REAQ | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-ORRE | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-OROR | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-ORGO | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GORE | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GOOR | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GOGO | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GOGR | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GRRE | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GROR | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GRGO | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GRGR | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-AQRE | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-AQOR | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-AQGO | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-AQGR | 20 (40 μL) | 200 μL |
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| CCL14-MYH10-20-AQAQ | 20 (40 μL) | 200 μL |
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MYH10 Gene Summary
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Myosin Heavy Chain 10
Chromosome: CHR17: 8377529 -8534036
Locus: 17p13.1
CCL14 Gene Summary
This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009]
Gene Name: C-C Motif Chemokine Ligand 14
Chromosome: CHR17: 34310691 -34313764
Locus: 17q12
Gene Diseases
The CCL14 MYH10 Fusion has been associated with the following diseases:
| Disease Name |
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| Cholangiocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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