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CCL14-MYH10 Fusion FISH Probe

The CCL14-MYH10 Fusion FISH Probe is used to confirm a fusion of the CCL14 and MYH10 genes. The fusion of the CCL14 and MYH10 genes has been associated with Cholangiocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CCL14-MYH10-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CCL14-MYH10-20-RERE 20 (40 μL) 200 μL
CCL14-MYH10-20-REOR 20 (40 μL) 200 μL
CCL14-MYH10-20-REGO 20 (40 μL) 200 μL
CCL14-MYH10-20-REGR 20 (40 μL) 200 μL
CCL14-MYH10-20-REAQ 20 (40 μL) 200 μL
CCL14-MYH10-20-ORRE 20 (40 μL) 200 μL
CCL14-MYH10-20-OROR 20 (40 μL) 200 μL
CCL14-MYH10-20-ORGO 20 (40 μL) 200 μL
CCL14-MYH10-20-ORAQ 20 (40 μL) 200 μL
CCL14-MYH10-20-GORE 20 (40 μL) 200 μL
CCL14-MYH10-20-GOOR 20 (40 μL) 200 μL
CCL14-MYH10-20-GOGO 20 (40 μL) 200 μL
CCL14-MYH10-20-GOGR 20 (40 μL) 200 μL
CCL14-MYH10-20-GOAQ 20 (40 μL) 200 μL
CCL14-MYH10-20-GRRE 20 (40 μL) 200 μL
CCL14-MYH10-20-GROR 20 (40 μL) 200 μL
CCL14-MYH10-20-GRGO 20 (40 μL) 200 μL
CCL14-MYH10-20-GRGR 20 (40 μL) 200 μL
CCL14-MYH10-20-GRAQ 20 (40 μL) 200 μL
CCL14-MYH10-20-AQRE 20 (40 μL) 200 μL
CCL14-MYH10-20-AQOR 20 (40 μL) 200 μL
CCL14-MYH10-20-AQGO 20 (40 μL) 200 μL
CCL14-MYH10-20-AQGR 20 (40 μL) 200 μL
CCL14-MYH10-20-AQAQ 20 (40 μL) 200 μL

MYH10 Gene Summary

This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Gene Name: Myosin Heavy Chain 10

Chromosome: CHR17: 8377529 -8534036

Locus: 17p13.1

CCL14 Gene Summary

This gene, chemokine (C-C motif) ligand 14, is one of several CC cytokine genes clustered on 17q11.2. The CC cytokines are secreted proteins characterized by two adjacent cysteines. The cytokine encoded by this gene induces changes in intracellular calcium concentration and enzyme release in monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Read-through transcripts are also expressed that include exons from the upstream cytokine gene, chemokine (C-C motif) ligand 15, and are represented as GeneID: 348249. [provided by RefSeq, Dec 2009]

Gene Name: C-C Motif Chemokine Ligand 14

Chromosome: CHR17: 34310691 -34313764

Locus: 17q12

Gene Diseases

The CCL14 MYH10 Fusion has been associated with the following diseases:

Disease Name
Cholangiocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.