CCDC88B-AKR1C1 Fusion FISH Probe
The CCDC88B-AKR1C1 Fusion FISH Probe is used to confirm a fusion of the CCDC88B and AKR1C1 genes. The fusion of the CCDC88B and AKR1C1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCDC88B-AKR1C1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-RERE | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-REOR | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-REGO | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-REGR | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-REAQ | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-ORRE | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-OROR | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-ORGO | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GORE | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GOOR | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GOGO | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GOGR | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GRRE | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GROR | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GRGO | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GRGR | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-AQRE | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-AQOR | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-AQGO | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-AQGR | 20 (40 μL) | 200 μL |
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| CCDC88B-AKR1C1-20-AQAQ | 20 (40 μL) | 200 μL |
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AKR1C1 Gene Summary
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
Gene Name: Aldo-keto Reductase Family 1 Member C1
Chromosome: CHR10: 5005453 -5020158
Locus: 10p15.1
CCDC88B Gene Summary
This gene encodes a member of the hook-related protein family. Members of this family are characterized by an N-terminal potential microtubule binding domain, a central coiled-coiled and a C-terminal Hook-related domain. The encoded protein may be involved in linking organelles to microtubules. [provided by RefSeq, Oct 2009]
Gene Name: Coiled-coil Domain Containing 88B
Chromosome: CHR11: 64107689 -64125006
Locus: 11q13.1
Gene Diseases
The CCDC88B AKR1C1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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