CCDC73-CAV1 Fusion FISH Probe
The CCDC73-CAV1 Fusion FISH Probe is used to confirm a fusion of the CCDC73 and CAV1 genes. The fusion of the CCDC73 and CAV1 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCDC73-CAV1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-RERE | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-REOR | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-REGO | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-REGR | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-REAQ | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-ORRE | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-OROR | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-ORGO | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GORE | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GOOR | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GOGO | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GOGR | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GRRE | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GROR | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GRGO | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GRGR | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-AQRE | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-AQOR | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-AQGO | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-AQGR | 20 (40 μL) | 200 μL |
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| CCDC73-CAV1-20-AQAQ | 20 (40 μL) | 200 μL |
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CAV1 Gene Summary
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]
Gene Name: Caveolin 1
Chromosome: CHR7: 116164838 -116201239
Locus: 7q31.2
CCDC73 Gene Summary
The Coiled-coil Domain Containing 73 (CCDC73) gene is located on chr11 :32623625-32816187 at 11p13.
Gene Name: Coiled-coil Domain Containing 73
Chromosome: CHR11: 32623625 -32816187
Locus: 11p13
Gene Diseases
The CCDC73 CAV1 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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