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CCDC50-LSAMP Fusion FISH Probe

The CCDC50-LSAMP Fusion FISH Probe is used to confirm a fusion of the CCDC50 and LSAMP genes. The fusion of the CCDC50 and LSAMP genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CCDC50-LSAMP-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
CCDC50-LSAMP-20-RERE 20 (40 μL) 200 μL
CCDC50-LSAMP-20-REOR 20 (40 μL) 200 μL
CCDC50-LSAMP-20-REGO 20 (40 μL) 200 μL
CCDC50-LSAMP-20-REGR 20 (40 μL) 200 μL
CCDC50-LSAMP-20-REAQ 20 (40 μL) 200 μL
CCDC50-LSAMP-20-ORRE 20 (40 μL) 200 μL
CCDC50-LSAMP-20-OROR 20 (40 μL) 200 μL
CCDC50-LSAMP-20-ORGO 20 (40 μL) 200 μL
CCDC50-LSAMP-20-ORAQ 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GORE 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GOOR 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GOGO 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GOGR 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GOAQ 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GRRE 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GROR 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GRGO 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GRGR 20 (40 μL) 200 μL
CCDC50-LSAMP-20-GRAQ 20 (40 μL) 200 μL
CCDC50-LSAMP-20-AQRE 20 (40 μL) 200 μL
CCDC50-LSAMP-20-AQOR 20 (40 μL) 200 μL
CCDC50-LSAMP-20-AQGO 20 (40 μL) 200 μL
CCDC50-LSAMP-20-AQGR 20 (40 μL) 200 μL
CCDC50-LSAMP-20-AQAQ 20 (40 μL) 200 μL

LSAMP Gene Summary

This gene encodes a member of the immunoglobulin LAMP, OBCAM and neurotrimin (IgLON) family of proteins. The encoded preproprotein is proteolytically processed to generate a neuronal surface glycoprotein. This protein may act as a selective homophilic adhesion molecule during axon guidance and neuronal growth in the developing limbic system. The encoded protein may also function as a tumor suppressor and may play a role in neuropsychiatric disorders. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Gene Name: Limbic System-associated Membrane Protein

Chromosome: CHR3: 115521209 -116164385

Locus: 3q13.31

CCDC50 Gene Summary

This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

Gene Name: Coiled-coil Domain Containing 50

Chromosome: CHR3: 191046873 -191116459

Locus: 3q28

Gene Diseases

The CCDC50 LSAMP Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.