CCDC3-FXYD1 Fusion FISH Probe
The CCDC3-FXYD1 Fusion FISH Probe is used to confirm a fusion of the CCDC3 and FXYD1 genes. The fusion of the CCDC3 and FXYD1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCDC3-FXYD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-RERE | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-REOR | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-REGO | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-REGR | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-REAQ | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-ORRE | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-OROR | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-ORGO | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GORE | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GOOR | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GOGO | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GOGR | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GRRE | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GROR | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GRGO | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GRGR | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-AQRE | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-AQOR | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-AQGO | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-AQGR | 20 (40 μL) | 200 μL |
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| CCDC3-FXYD1-20-AQAQ | 20 (40 μL) | 200 μL |
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FXYD1 Gene Summary
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity. Transcript variants with different 5' UTR sequences have been described in the literature. [provided by RefSeq, Jul 2008]
Gene Name: FXYD Domain Containing Ion Transport Regulator 1
Chromosome: CHR19: 35629731 -35633954
Locus: 19q13.12
CCDC3 Gene Summary
The Coiled-coil Domain Containing 3 (CCDC3) gene is located on chr10 :12938624-13043704 at 10p13.
Gene Name: Coiled-coil Domain Containing 3
Chromosome: CHR10: 12938624 -13043704
Locus: 10p13
Gene Diseases
The CCDC3 FXYD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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