CCDC149-RBPJ Fusion FISH Probe
The CCDC149-RBPJ Fusion FISH Probe is used to confirm a fusion of the CCDC149 and RBPJ genes. The fusion of the CCDC149 and RBPJ genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCDC149-RBPJ-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-RERE | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-REOR | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-REGO | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-REGR | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-REAQ | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-ORRE | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-OROR | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-ORGO | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GORE | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GOOR | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GOGO | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GOGR | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GRRE | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GROR | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GRGO | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GRGR | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-AQRE | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-AQOR | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-AQGO | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-AQGR | 20 (40 μL) | 200 μL |
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| CCDC149-RBPJ-20-AQAQ | 20 (40 μL) | 200 μL |
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RBPJ Gene Summary
The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013]
Gene Name: Recombination Signal Binding Protein For Immunoglobulin Kappa J Region
Chromosome: CHR4: 26321331 -26433278
Locus: 4p15.2
CCDC149 Gene Summary
The Coiled-coil Domain Containing 149 (CCDC149) gene is located on chr4 :24807738-24981826 at 4p15.2.
Gene Name: Coiled-coil Domain Containing 149
Chromosome: CHR4: 24807738 -24981826
Locus: 4p15.2
Gene Diseases
The CCDC149 RBPJ Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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