CCAR1-HNRNPH3 Fusion FISH Probe
The CCAR1-HNRNPH3 Fusion FISH Probe is used to confirm a fusion of the CCAR1 and HNRNPH3 genes. The fusion of the CCAR1 and HNRNPH3 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CCAR1-HNRNPH3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-RERE | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-REOR | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-REGO | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-REGR | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-REAQ | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-ORRE | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-OROR | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-ORGO | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-ORAQ | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GORE | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GOOR | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GOGO | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GOGR | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GOAQ | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GRRE | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GROR | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GRGO | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GRGR | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-GRAQ | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-AQRE | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-AQOR | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-AQGO | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-AQGR | 20 (40 μL) | 200 μL |
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| CCAR1-HNRNPH3-20-AQAQ | 20 (40 μL) | 200 μL |
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HNRNPH3 Gene Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008]
Gene Name: Heterogeneous Nuclear Ribonucleoprotein H3
Chromosome: CHR10: 70091767 -70102953
Locus: 10q21.3
CCAR1 Gene Summary
The Cell Division Cycle And Apoptosis Regulator 1 (CCAR1) gene is located on chr10 :70480970-70551309 at 10q21.3.
Gene Name: Cell Division Cycle And Apoptosis Regulator 1
Chromosome: CHR10: 70480970 -70551309
Locus: 10q21.3
Gene Diseases
The CCAR1 HNRNPH3 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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