CC2D1A-RRBP1 Fusion FISH Probe
The CC2D1A-RRBP1 Fusion FISH Probe is used to confirm a fusion of the CC2D1A and RRBP1 genes. The fusion of the CC2D1A and RRBP1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CC2D1A-RRBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-RERE | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-REOR | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-REGO | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-REGR | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-OROR | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GORE | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GROR | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| CC2D1A-RRBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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RRBP1 Gene Summary
This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012]
Gene Name: Ribosome Binding Protein 1
Chromosome: CHR20: 17594322 -17662928
Locus: 20p12.1
CC2D1A Gene Summary
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in a nonsyndromic form of cognitive disability (MRT3). [provided by RefSeq, Jul 2017]
Gene Name: Coiled-coil And C2 Domain Containing 1A
Chromosome: CHR19: 14016955 -14041693
Locus: 19p13.12
Gene Diseases
The CC2D1A RRBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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